Insulitis and Exocrinitis in Autoantibody-positive Nondiabetic Individuals: Role of HLA Genotypes
Contrary to stage 3 T1D, autoantibody-positive donors had normal β-cell mass and no significant insulitis, suggesting heterogeneity in the progression of autoimmunity, even in the presence of genetic risk, rather than a uniform slow-progressing process.
Authors
- Danièle Dubois‐Laforgue (ORCID: https://orcid.org/0000-0003-3287-6309)
- Étienne Larger (ORCID: https://orcid.org/0000-0002-1017-1845)
- Roberto Mallone (ORCID: https://orcid.org/0000-0002-9846-8861)
- Marc Diedisheim (ORCID: https://orcid.org/0000-0002-0418-1107)
- Alberto Pugliese
Institutions
- Centre National de la Recherche Scientifique (FR)
- Inserm (FR)
- Université Paris Cité (FR)
- Indiana Biosciences Research Institute (US)
- Institut Necker Enfants Malades (FR)
- Hôpital Cochin (FR)
- City of Hope (US)
- Institut Cochin (FR)
- Institute of Nutrition, Metabolism and Diabetes (CA)
- Beckman Research Institute
Publication Details
- Journal
- The Journal of Clinical Endocrinology & Metabolism
- Published
- 2025-01-27
- DOI
- https://doi.org/10.1210/clinem/dgaf039
- Citations
- 3
- Primary Topic
- Diabetes and associated disorders
- Type
- article
- Field-Weighted Citation Impact
- 5.45