A multicenter, randomized, double-blind trial comparing LY01011, a biosimilar, with denosumab (Xgeva®) in patients with bone metastasis from solid tumors

This study demonstrated the equivalent efficacy and safety of LY01011 to denosumab in patients with BM.

Authors

Institutions

Publication Details

Journal
Journal of bone oncology
Published
2025-01-29
DOI
https://doi.org/10.1016/j.jbo.2025.100661
Citations
1
Primary Topic
Bone health and treatments
Type
article
Field-Weighted Citation Impact
1.05
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article

A multicenter, randomized, double-blind trial comparing LY01011, a biosimilar, with denosumab (Xgeva®) in patients with bone metastasis from solid tumors

Ou Jiang, Jingfen Wang, Peijian Peng, Weihua Yang et al.
1 citations
Journal of bone oncology
Bone health and treatments
1.05
article

A multicenter, randomized, double-blind trial comparing LY01011, a biosimilar, with denosumab (Xgeva®) in patients with bone metastasis from solid tumors

Ou Jiang, Jingfen Wang, Peijian Peng, Weihua Yang, Kaijian Lei, Ming Zhou, Zhé Hóu, Dongqing Lv, Changlin Dou, Baihui Hu, Hongjie Xu, Qingshan Li, Zhendong Chen, Xia Yuan, Hongmei Sun, Song Zheng, Xicheng Wang, Xichun Hu, Lili Sheng, Minghong Bi, Xiumei Dai, Yan Yu, Panpan Zhuang, Aiping Zeng, Chang-Lu Hu, Mingli Ni, Tienan Yi, Mingchuan Zhao, Zhaoping Su, Huaqiu Shi
article en
1 citations

Abstract

This study demonstrated the equivalent efficacy and safety of LY01011 to denosumab in patients with BM.

Journal of bone oncologyVol. 51
Jiamusi University (CN), Harbin Medical University (CN), Sun Yat-sen University (CN), Bengbu Medical College (CN), Anhui Medical University (CN), Wenzhou Medical University (CN), Fudan University Shanghai Cancer Center (CN), Hue University (VN), Linyi People's Hospital (CN), Shanxi Provincial Cancer Hospital (CN), Third Affiliated Hospital of Harbin Medical University (CN), Chengde Medical University (CN), Fifth Affiliated Hospital of Sun Yat-sen University (CN), Neijiang Normal University (CN), First Affiliated Hospital of Guangdong Pharmaceutical University (CN), Xiangyang Central Hospital (CN), Luoyang Central Hospital Affiliated to Zhengzhou University (CN), Beike Biotechnology (China) (CN), Anhui Provincial Hospital (CN), Linzhou Cancer Hospital (CN), Xuzhou Central Hospital (CN), First Affiliated Hospital of Gannan Medical University (CN), Luye Pharma (China) (CN), Huizhou Central People's Hospital (CN), Second Affiliated Hospital of Anhui Medical University (CN), First Affiliated Hospital of Bengbu Medical College (CN), Tumor Hospital of Guangxi Medical University (CN), Second People’s Hospital of Yibin (CN), Zhejiang Taizhou Hospital (CN), First Affiliated Hospital of Wannan Medical College (CN)
Good health and well-being
Openalex Percentile: Top 26%
Bone health and treatments
1.05
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