A multicenter, randomized, double-blind trial comparing LY01011, a biosimilar, with denosumab (Xgeva®) in patients with bone metastasis from solid tumors
This study demonstrated the equivalent efficacy and safety of LY01011 to denosumab in patients with BM.
Authors
- Ou Jiang (ORCID: https://orcid.org/0000-0002-3455-9676)
- Jingfen Wang
- Peijian Peng
- Weihua Yang (ORCID: https://orcid.org/0000-0001-5468-758X)
- Kaijian Lei (ORCID: https://orcid.org/0000-0002-2008-3726)
- Ming Zhou (ORCID: https://orcid.org/0000-0003-4101-3185)
- Zhé Hóu (ORCID: https://orcid.org/0000-0001-7164-0580)
- Dongqing Lv (ORCID: https://orcid.org/0000-0001-8226-9596)
- Changlin Dou (ORCID: https://orcid.org/0000-0001-8221-8086)
- Baihui Hu
- Hongjie Xu (ORCID: https://orcid.org/0000-0003-0143-3804)
- Qingshan Li (ORCID: https://orcid.org/0000-0002-5564-0860)
- Zhendong Chen (ORCID: https://orcid.org/0000-0002-2035-635X)
- Xia Yuan (ORCID: https://orcid.org/0000-0003-3210-4691)
- Hongmei Sun (ORCID: https://orcid.org/0000-0003-1003-2404)
- Song Zheng (ORCID: https://orcid.org/0000-0002-5870-0515)
- Xicheng Wang (ORCID: https://orcid.org/0000-0001-6677-850X)
- Xichun Hu (ORCID: https://orcid.org/0000-0002-9892-699X)
- Lili Sheng (ORCID: https://orcid.org/0000-0002-1142-6512)
- Minghong Bi
- Xiumei Dai (ORCID: https://orcid.org/0000-0002-2904-8249)
- Yan Yu (ORCID: https://orcid.org/0000-0001-5598-763X)
- Panpan Zhuang
- Aiping Zeng
- Chang-Lu Hu
- Mingli Ni
- Tienan Yi (ORCID: https://orcid.org/0009-0008-8678-4841)
- Mingchuan Zhao
- Zhaoping Su
- Huaqiu Shi
Institutions
- Jiamusi University (CN)
- Harbin Medical University (CN)
- Sun Yat-sen University (CN)
- Bengbu Medical College (CN)
- Anhui Medical University (CN)
- Wenzhou Medical University (CN)
- Fudan University Shanghai Cancer Center (CN)
- Hue University (VN)
- Linyi People's Hospital (CN)
- Shanxi Provincial Cancer Hospital (CN)
- Third Affiliated Hospital of Harbin Medical University (CN)
- Chengde Medical University (CN)
- Fifth Affiliated Hospital of Sun Yat-sen University (CN)
- Neijiang Normal University (CN)
- First Affiliated Hospital of Guangdong Pharmaceutical University (CN)
- Xiangyang Central Hospital (CN)
- Luoyang Central Hospital Affiliated to Zhengzhou University (CN)
- Beike Biotechnology (China) (CN)
- Anhui Provincial Hospital (CN)
- Linzhou Cancer Hospital (CN)
- Xuzhou Central Hospital (CN)
- First Affiliated Hospital of Gannan Medical University (CN)
- Luye Pharma (China) (CN)
- Huizhou Central People's Hospital (CN)
- Second Affiliated Hospital of Anhui Medical University (CN)
- First Affiliated Hospital of Bengbu Medical College (CN)
- Tumor Hospital of Guangxi Medical University (CN)
- Second People’s Hospital of Yibin (CN)
- Zhejiang Taizhou Hospital (CN)
- First Affiliated Hospital of Wannan Medical College (CN)
Publication Details
- Journal
- Journal of bone oncology
- Published
- 2025-01-29
- DOI
- https://doi.org/10.1016/j.jbo.2025.100661
- Citations
- 1
- Primary Topic
- Bone health and treatments
- Type
- article
- Field-Weighted Citation Impact
- 1.05