Comparative Analysis of <scp>4NQO</scp> ‐ and Ethanol‐Induced Oral Epithelial Dysplasia and Oral Squamous Cell Carcinoma in Male and Female Mice: Association With Peripheral Blood Inflammatory Markers
The low incidence of 4NQO- and ethanol-induced OSCC in females indicates that the sex bias in OSCC may not be associated with extrinsic risk factors alone. Neutrophil and lymphocyte counts, NRL, and SII were significantly altered during multistep carcinogenesis and thus could be explored as biomarkers for ED and OSCC development.
Authors
- Rafael Borges Rosa (ORCID: https://orcid.org/0000-0003-0681-6433)
- Emilene Ferreira de Castro (ORCID: https://orcid.org/0000-0002-4189-0041)
- Israel Marinho Pereira (ORCID: https://orcid.org/0000-0003-1035-1253)
- Paulo Rogério de Faria (ORCID: https://orcid.org/0000-0003-2650-3960)
- Sérgio Vitorino Cardoso (ORCID: https://orcid.org/0000-0003-1809-0617)
- Marcos Reinaldo da Silva (ORCID: https://orcid.org/0000-0002-4389-5428)
- I Jesus (ORCID: https://orcid.org/0009-0003-6578-116X)
- Anaíra Ribeiro Guedes Fonseca Costa (ORCID: https://orcid.org/0000-0001-7560-6531)
- Adriano Mota Loyola (ORCID: https://orcid.org/0000-0001-9707-9365)
- Débora de Oliveira Santos (ORCID: https://orcid.org/0000-0002-8895-9907)
Institutions
- Fundação Oswaldo Cruz (BR)
- Universidade Federal de Uberlândia (BR)
Publication Details
- Journal
- Journal of Oral Pathology and Medicine
- Published
- 2025-01-27
- DOI
- https://doi.org/10.1111/jop.13602
- Citations
- 1
- Primary Topic
- Head and Neck Cancer Studies
- Type
- article
- Field-Weighted Citation Impact
- 1.85
Funders
- Coordenação de Aperfeiçoamento de Pessoal de Nível Superior
- Conselho Nacional de Desenvolvimento Científico e Tecnológico
- Fundação de Amparo à Pesquisa do Estado de Minas Gerais