Evolution of photodynamic therapy application in the treatment of malignant neoplasms

Photodynamic therapy (PDT) is a modern non-invasive technique of antitumor treatment. In its basis local or systemic application light-sensitive compound-photosensitizer (FS), which is selectively nakuplen in pathological tissue. In the interaction with the light of a certain length of the wave in the presence of oxygen in the fabric of the triggered photochemical process, driving to the gibel cell and activation of the immune response. Accumulation of FS in the affected tissues and targeted light allows to achieve high selectivity of action and minimal damage to surrounding tissues. Absence of resistance to PDT and possibility of combination with traditional methods of tumor treatment (surgical, radiation, systemic antitumor therapy) increase efficiency of PDT use in treatment of malignant neoplasms of different localizations, including palliative care.