Course of malignant pheochromocytoma. Clinical case

Pheochromocytomas (PH) are rare catecholamine-secreting neuroendocrine tumors, which are hereditary in almost 40% of cases. Symptoms of pheochromocytoma are caused by excessive production of catecholamines or mass effect. The frequency of metastasis of PH can reach 25%. Patients with pheochromocytoma have a 4-fold higher risk of developing other malignant neoplasms (in men, liver cancer, biliary tract cancer, and central nervous system tumors are mainly diagnosed). This article discusses a case of primary multiple change pheochromocytoma and gastric cancer. The main objective of the article is to increase clinical alertness and relevance of the problems of differential diagnosis and treatment in the progression of pheochromocytoma after a long relapse-free period.

Authors

Publication Details

Journal
Clinical Case in Oncology
Published
2025-01-27
DOI
https://doi.org/10.62546/3034-1477-2024-2-3-53-61
Primary Topic
Adrenal and Paraganglionic Tumors
Type
article
Field-Weighted Citation Impact
0.00
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article

Course of malignant pheochromocytoma. Clinical case

M. M Salnikova
Clinical Case in Oncology
Adrenal and Paraganglionic Tumors
article

Course of malignant pheochromocytoma. Clinical case

M. M Salnikova
article en

Abstract

Pheochromocytomas (PH) are rare catecholamine-secreting neuroendocrine tumors, which are hereditary in almost 40% of cases. Symptoms of pheochromocytoma are caused by excessive production of catecholamines or mass effect. The frequency of metastasis of PH can reach 25%. Patients with pheochromocytoma have a 4-fold higher risk of developing other malignant neoplasms (in men, liver cancer, biliary tract cancer, and central nervous system tumors are mainly diagnosed). This article discusses a case of primary multiple change pheochromocytoma and gastric cancer. The main objective of the article is to increase clinical alertness and relevance of the problems of differential diagnosis and treatment in the progression of pheochromocytoma after a long relapse-free period.

Clinical Case in OncologyVol. 2(3)
Openalex Percentile: Top 97%
Adrenal and Paraganglionic Tumors
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