Screening potential antileukemia ingredients from sweet potato: integration of metabolomics analysis, network pharmacology, and experimental validation
In summary, sweet potato leaves extract possesses an antileukemic effect while cynaroside, nepitrin, and yuanhuanin demonstrate potential as treatments for AML.
Authors
- Yan Zeng (ORCID: https://orcid.org/0000-0002-4083-0127)
- Ling Guo (ORCID: https://orcid.org/0000-0003-1986-3175)
- Lianling Xu
- Yang You (ORCID: https://orcid.org/0000-0002-5282-375X)
- Zhenglu Duan (ORCID: https://orcid.org/0000-0003-2901-7992)
- Qulian Guo (ORCID: https://orcid.org/0000-0002-5958-2258)
- Jing Liu (ORCID: https://orcid.org/0000-0001-5207-7614)
- Wenjun Liu (ORCID: https://orcid.org/0000-0002-7205-0598)
- Miao Zhang (ORCID: https://orcid.org/0000-0003-4912-2570)
- Yanling Jin (ORCID: https://orcid.org/0009-0004-6546-5201)
- Kaixuan Zeng
Institutions
- Chinese Academy of Sciences (CN)
- Southwest Medical University (CN)
- Affiliated Hospital of Southwest Medical University (CN)
- Chengdu Institute of Biology (CN)
Publication Details
- Journal
- Frontiers in Nutrition
- Published
- 2025-01-27
- DOI
- https://doi.org/10.3389/fnut.2025.1518525
- Citations
- 2
- Primary Topic
- CRISPR and Genetic Engineering
- Type
- article
- Field-Weighted Citation Impact
- 1.61