Persistent penumbral profiles indicate a potentially good outcome in acute stroke patients without major reperfusion
Persistent penumbra in acute stroke patients without major reperfusion was generally associated with a better clinical outcome. This evidence suggested that there were patients with persistent hemodynamic support, for whom major reperfusion might not be pivotal to achieve a good clinical outcome. How to identify these patients and what treatment strategy can be made to stabilize the hemodynamics need future investigation.Data access statement:Anonymized data not published within this article will be made available at the request of qualified investigators whose proposal of data use has been approved by an independent review committee.
Authors
- Xin Cheng (ORCID: https://orcid.org/0000-0001-7816-0547)
- Andrew Bivard (ORCID: https://orcid.org/0000-0001-7762-5832)
- Chushuang Chen (ORCID: https://orcid.org/0000-0001-6014-846X)
- Christopher Levi (ORCID: https://orcid.org/0000-0002-9474-796X)
- Lan Hong (ORCID: https://orcid.org/0000-0002-4002-4627)
- Longting Lin (ORCID: https://orcid.org/0000-0001-7104-9846)
- Ya Su (ORCID: https://orcid.org/0000-0002-2689-3148)
- Yifeng Ling (ORCID: https://orcid.org/0000-0002-9813-5813)
- Qiang Dong (ORCID: https://orcid.org/0000-0002-3814-1883)
- Mark Parsons
Institutions
- The Royal Melbourne Hospital (AU)
- The University of Melbourne (AU)
- Fudan University (CN)
- John Hunter Hospital (AU)
- UNSW Sydney (AU)
- Huashan Hospital (CN)
- South Western Sydney Local Health District (AU)
- State Key Laboratory of Medical Neurobiology
- University of Newcastle Australia (AU)
Publication Details
- Journal
- International Journal of Stroke
- Published
- 2025-01-29
- DOI
- https://doi.org/10.1177/17474930251318921
- Citations
- 2
- Primary Topic
- Acute Ischemic Stroke Management
- Type
- article
- Field-Weighted Citation Impact
- 2.71
Funders
- Shanghai Municipal Health Commission
- National Natural Science Foundation of China