Large language models for diabetes training: a prospective study
Diabetes poses a considerable global health challenge, with varying levels of diabetes knowledge among healthcare professionals, highlighting the importance of diabetes training. Large Language Models (LLMs) provide new insights into diabetes training, but their performance in diabetes-related queries remains uncertain, especially outside the English language like Chinese. We first evaluated the performance of ten LLMs: ChatGPT-3.5, ChatGPT-4.0, Google Bard, LlaMA-7B, LlaMA2-7B, Baidu ERNIE Bot, Ali Tongyi Qianwen, MedGPT, HuatuoGPT, and Chinese LlaMA2-7B on diabetes-related queries, based on the Chinese National Certificate Examination for Primary Diabetes Care in China (NCE-CPDC) and the English Specialty Certificate Examination in Endocrinology and Diabetes of Membership of the Royal College of Physicians of the United Kingdom. Second, we assessed the training of primary care physicians (PCPs) without and with the assistance of ChatGPT-4.0 in the NCE-CPDC examination to ascertain the reliability of LLMs as medical assistants. We found that ChatGPT-4.0 outperformed other LLMs in the English examination, achieving a passing accuracy of 62.50%, which was significantly higher than that of Google Bard, LlaMA-7B, and LlaMA2-7B. For the NCE-CPFC examination, ChatGPT-4.0, Ali Tongyi Qianwen, Baidu ERNIE Bot, Google Bard, MedGPT, and ChatGPT-3.5 successfully passed, whereas LlaMA2-7B, HuatuoGPT, Chinese LLaMA2-7B, and LlaMA-7B failed. ChatGPT-4.0 (84.82%) surpassed all PCPs and assisted most PCPs in the NCE-CPDC examination (improving by 1 %-6.13%). In summary, LLMs demonstrated outstanding competence for diabetes-related questions in both the Chinese and English language, and hold great potential to assist future diabetes training for physicians globally.
Authors
- Zhouyu Guan (ORCID: https://orcid.org/0009-0008-5102-0067)
- Elif Ilhan Ekinci (ORCID: https://orcid.org/0000-0003-2372-395X)
- Weiping Jia (ORCID: https://orcid.org/0000-0002-6244-2168)
- Di Cheng (ORCID: https://orcid.org/0000-0001-9388-376X)
- Yingfeng Zheng (ORCID: https://orcid.org/0000-0002-9952-6445)
- Charumathi Sabanayagam (ORCID: https://orcid.org/0000-0002-4042-4719)
- Yuqian Bao (ORCID: https://orcid.org/0000-0002-4754-3470)
- Ya Xing Wang (ORCID: https://orcid.org/0000-0003-2749-7793)
- Huating Li (ORCID: https://orcid.org/0000-0003-0526-5545)
- Carol Y. Cheung (ORCID: https://orcid.org/0000-0002-9672-1819)
- Ruhan Liu (ORCID: https://orcid.org/0000-0002-0281-8039)
- Justin Basile Echouffo-Tcheugui (ORCID: https://orcid.org/0000-0002-8460-1617)
- Ching‐Yu Cheng (ORCID: https://orcid.org/0000-0003-0655-885X)
- Hongwei Ji
- Liang Wu (ORCID: https://orcid.org/0000-0002-3763-1274)
- Zehua Jiang (ORCID: https://orcid.org/0000-0001-9100-0986)
- Leonor Corsino
- Cynthia Ciwei Lim (ORCID: https://orcid.org/0000-0003-0021-4861)
- Nestoras Mathioudakis (ORCID: https://orcid.org/0000-0002-0210-655X)
- Yong Mong Bee (ORCID: https://orcid.org/0000-0002-5482-2646)
- Hong Chang Tan
- Yuexing Liu (ORCID: https://orcid.org/0000-0003-4369-1131)
- Tien Yin Wong (ORCID: https://orcid.org/0000-0002-8448-1264)
- Gavin Siew Wei Tan (ORCID: https://orcid.org/0000-0001-5383-7136)
- Yih Chung Tham (ORCID: https://orcid.org/0000-0002-6752-797X)
- David Charles Klonoff (ORCID: https://orcid.org/0000-0001-6394-6862)
- Weibing Wu (ORCID: https://orcid.org/0000-0001-5655-8861)
- Lee‐Ling Lim (ORCID: https://orcid.org/0000-0002-6214-6924)
- Rafael Simó (ORCID: https://orcid.org/0000-0003-0475-3096)
- Yong Wang (ORCID: https://orcid.org/0000-0001-6002-4299)
- Jiajia Li (ORCID: https://orcid.org/0000-0001-8158-3970)
- Haoxuan Li (ORCID: https://orcid.org/0000-0002-3483-4914)
- Jihong Wang (ORCID: https://orcid.org/0000-0001-6965-7949)
- Zhen Li (ORCID: https://orcid.org/0000-0001-8145-460X)
- Chun Cai (ORCID: https://orcid.org/0000-0001-8725-5433)
- Bin Sheng
- Lijuan Mao (ORCID: https://orcid.org/0000-0002-9160-7697)
- Tingting Hu
Institutions
- Qingdao University (CN)
- Sun Yat-sen University (CN)
- Duke University (US)
- Chinese University of Hong Kong (HK)
- Shanghai University of Sport (CN)
- Singapore General Hospital (SG)
- Singapore National Eye Center (SG)
- Affiliated Hospital of Qingdao University (CN)
- Singapore Eye Research Institute (SG)
- Mills Peninsula Health Services (US)
Publication Details
- Journal
- Science Bulletin
- Published
- 2025-01-27
- DOI
- https://doi.org/10.1016/j.scib.2025.01.034
- Citations
- 16
- Primary Topic
- Artificial Intelligence in Healthcare and Education
- Type
- article
- Field-Weighted Citation Impact
- 10.47
Funders
- National Natural Science Foundation of China