RNA binding protein ILF3 increases CEP55 mRNA stability to enhance malignant potential of breast cancer cells and suppress ferroptosis
Our observations indicate that the depletion of ILF3 impairs the malignant potential of BC cells and promotes their ferroptosis by downregulating CEP55 expression. Silencing ILF3 or CEP55 could represent a potential therapeutic strategy for BC treatment.
Authors
- Si‐Min Ruan
- Yuan Luo (ORCID: https://orcid.org/0000-0003-1198-3877)
- Sheng Chen (ORCID: https://orcid.org/0000-0003-3526-7808)
- Guosen Su
- Guoxing Huang (ORCID: https://orcid.org/0009-0004-3498-1465)
Institutions
- Gaozhou People's Hospital (CN)
Publication Details
- Journal
- Hereditas
- Published
- 2025-01-27
- DOI
- https://doi.org/10.1186/s41065-025-00372-0
- Citations
- 3
- Primary Topic
- Ferroptosis and cancer prognosis
- Type
- article
- Field-Weighted Citation Impact
- 4.56