JAK/STAT3 signaling promotes pain and depression-like behaviors in rats with bone cancer pain by regulating Th17 cell differentiation
Our study showed that targeting JAK/STAT3 signaling alleviated pain- and depression-like behaviors in rats with BCP by inhibiting Th17 cell differentiation.
Authors
- Xiaohui Chen (ORCID: https://orcid.org/0000-0002-1864-6729)
- Daoyi Lin
- Jianghu Chen (ORCID: https://orcid.org/0000-0001-9450-7782)
- Honghong Zhang
- Jundan Jiang (ORCID: https://orcid.org/0000-0002-0321-4667)
- Pinzhong Chen (ORCID: https://orcid.org/0000-0001-7649-1801)
- Mingxue Lin (ORCID: https://orcid.org/0000-0003-1430-5035)
- Yingying Wang (ORCID: https://orcid.org/0000-0003-4363-8779)
- Xiaochun Zheng (ORCID: https://orcid.org/0000-0002-6483-6697)
- Danfeng Wang (ORCID: https://orcid.org/0009-0002-2059-3168)
- Shuyan Wu
Institutions
- Fujian Medical University (CN)
- Chinese Academy of Medical Sciences & Peking Union Medical College (CN)
- China-Japan Friendship Hospital (CN)
- Fujian Provincial Hospital (CN)
Publication Details
- Journal
- Brain Research Bulletin
- Published
- 2025-01-27
- DOI
- https://doi.org/10.1016/j.brainresbull.2025.111218
- Citations
- 6
- Primary Topic
- Psoriasis: Treatment and Pathogenesis
- Type
- article
- Field-Weighted Citation Impact
- 4.78