Effect of probiotics combined with immune checkpoint suppressors and chemotherapeutic agents on digestive system function, intestinal immunity and prognosis in patients with metastatic colorectal carcinoma: a quasi-experimental study
Immune checkpoint suppressors combined with chemotherapeutic agents or probiotic regimens can obviously enhance the prognosis of patients with metastatic colorectal carcinoma. This combination therapeutic strategy can balance the imbalanced intestinal flora, improve intestinal function, and lessen the incidence of adverse events, so it is worthy of clinical application and can lessen the incidence of adverse reactions.
Authors
- Fanfan Li (ORCID: https://orcid.org/0000-0003-1268-3702)
- Zhen Yang (ORCID: https://orcid.org/0009-0007-4072-7481)
- Min Yan (ORCID: https://orcid.org/0000-0002-3911-748X)
- Xiaolei Wang (ORCID: https://orcid.org/0000-0001-5441-0855)
- Yang Yang (ORCID: https://orcid.org/0000-0002-8392-2830)
- Chenghao Wang (ORCID: https://orcid.org/0000-0002-6730-1022)
- Fenfen Wei
- Yuxia Huang (ORCID: https://orcid.org/0000-0002-4741-2884)
Institutions
- Anhui Medical University (CN)
- Chizhou University (CN)
- Second Affiliated Hospital of Anhui Medical University (CN)
Publication Details
- Journal
- BMC Gastroenterology
- Published
- 2025-01-27
- DOI
- https://doi.org/10.1186/s12876-025-03604-9
- Citations
- 9
- Primary Topic
- Gut microbiota and health
- Type
- article
- Field-Weighted Citation Impact
- 7.25