Sequential Epidemiological Analyses of Real-World Data: A Tool for Prospective Drug Safety Surveillance from the Rofecoxib Example
Our prospective drug safety monitoring setup showed that the risk of MI could have been detected 3.5 years before the ultimate market withdrawal of rofecoxib. However, further research is needed to validate this approach.
Authors
- Saad Hanif Abbasi (ORCID: https://orcid.org/0000-0001-7677-1985)
- Lars Christian Lund (ORCID: https://orcid.org/0000-0001-8651-6072)
- Anton Pottegård (ORCID: https://orcid.org/0000-0001-9314-5679)
- Jesper Hallas (ORCID: https://orcid.org/0000-0002-8097-8708)
Institutions
- University of Southern Denmark (DK)
- Odense University Hospital (DK)
Publication Details
- Journal
- Drug Safety
- Published
- 2025-01-27
- DOI
- https://doi.org/10.1007/s40264-024-01512-7
- Citations
- 2
- Primary Topic
- Inflammatory mediators and NSAID effects
- Type
- article
- Field-Weighted Citation Impact
- 2.79
Funders
- Syddansk Universitet
- Danmarks Frie Forskningsfond