Studying Alzheimer’s disease through an integrative serum metabolomic and lipoproteomic approach
The identification of potential novel peripheral biomarkers of Alzheimer's disease, as proposed in this study, opens a new prospect for an innovative and minimally invasive method to identify AD in its very early stages. We proposed a novel approach able to sub-stratify MCI-AD patients identifying those associated with a faster rate of clinical progression.
Authors
- Lucilla Parnetti (ORCID: https://orcid.org/0000-0001-5722-3967)
- Alessia Vignoli (ORCID: https://orcid.org/0000-0003-4038-6596)
- Leonardo Tenori (ORCID: https://orcid.org/0000-0001-6438-059X)
- Claudio Luchinat (ORCID: https://orcid.org/0000-0003-2271-8921)
- Federico Paolini Paoletti (ORCID: https://orcid.org/0000-0001-9623-1900)
- Giovanni Bellomo (ORCID: https://orcid.org/0000-0003-0456-5650)
Institutions
- University of Perugia (IT)
- Interuniversity Consortium for Magnetic Resonance (IT)
- Giotto Biotech (Italy) (IT)
- University of Florence (IT)
Publication Details
- Journal
- Journal of Translational Medicine
- Published
- 2025-01-27
- DOI
- https://doi.org/10.1186/s12967-025-06148-4
- Citations
- 7
- Primary Topic
- Metabolomics and Mass Spectrometry Studies
- Type
- article
- Field-Weighted Citation Impact
- 5.64
Funders
- Parkinson's Foundation
- European Commission
- Associazione Italiana Ricerca Alzheimer
- Ministero dell'Università e della Ricerca