Single-cell analyses of intestinal epithelium reveal the dysregulation of gut immune microenvironment in systemic lupus erythematosus
Our high-resolution single-cell atlas enhances the understanding of the immune and structural milieu of intestinal epithelium in lupus and provides new insights into lupus pathogenesis mediated by intestinal immune dysregulation.
Authors
- Lianlian Ouyang
- Xiaoli Min (ORCID: https://orcid.org/0000-0002-8113-1541)
- Meiling Zheng (ORCID: https://orcid.org/0000-0003-3990-6777)
- Ming Zhao (ORCID: https://orcid.org/0000-0002-1320-1093)
- Qianjin Lu (ORCID: https://orcid.org/0000-0002-1504-4896)
- Wenjuan Jiang (ORCID: https://orcid.org/0000-0002-8430-556X)
- Shuang Yang (ORCID: https://orcid.org/0000-0003-3507-5937)
- Qiaolin Wang (ORCID: https://orcid.org/0000-0003-1397-6304)
- Lingyu Gao
- Zhi Hu
- Sujie Jia
- Yutong Wu
- Xiaoyun Chen (ORCID: https://orcid.org/0009-0004-6778-9787)
Institutions
- Central South University (CN)
- Chinese Academy of Medical Sciences & Peking Union Medical College (CN)
- Peking Union Medical College Hospital (CN)
- Chinese Academy of Medical Sciences Dermatology Hospital (CN)
- Second Xiangya Hospital of Central South University (CN)
Publication Details
- Journal
- Journal of Translational Medicine
- Published
- 2025-01-27
- DOI
- https://doi.org/10.1186/s12967-025-06147-5
- Citations
- 3
- Primary Topic
- Single-cell and spatial transcriptomics
- Type
- article
- Field-Weighted Citation Impact
- 2.42