Hypertrophic Cardiomyopathy and Cardiac Arrest Provoked by Low-Intensity Physical Activity – A Case Report

Hypertrophic cardiomyopathy (HCM) is the most prevalent genetic cardiac muscle disorder, predominantly inherited as an autosomal dominant trait due to mutations in sarcomere protein genes. Although HCM is genetically driven, its clinical presentation is marked by significant variability, with a wide range of phenotypic expressions. The condition often presents in childhood, with many patients facing a heightened risk of sudden cardiac death (SCD), particularly during high-intensity physical activity. Given the risks associated with HCM, particularly in the context of high-intensity competitive sports, it is generally recommended that affected individuals avoid such activities. However, even low-intensity physical activity has been associated with SCD, contributing to ongoing debates and unresolved questions within the field.