Predictive factors for axillary pathological complete response to neoadjuvant therapy in elderly breast cancer patients
This study indicates that initial cN0 stage and HER2 positivity can serve as independent predictive factors for apCR after NAT in elderly breast cancer patients. HER2-positive elderly patients with initial cN0 stage can be considered exempt from axillary lymph node dissection(ALND) after standard NAT.
Authors
- Purong Zhang (ORCID: https://orcid.org/0000-0003-4317-1355)
- Yaling Zeng (ORCID: https://orcid.org/0000-0002-6881-2385)
- Shiwei Liu (ORCID: https://orcid.org/0000-0002-6766-7518)
- Rui Wang (ORCID: https://orcid.org/0000-0003-3825-3620)
- Di Lu (ORCID: https://orcid.org/0000-0002-8724-3739)
- Yuying Wang (ORCID: https://orcid.org/0009-0007-9924-4409)
- X. Tu (ORCID: https://orcid.org/0000-0001-5845-7968)
Institutions
- North Sichuan Medical University (CN)
- University of Electronic Science and Technology of China (CN)
- Sichuan Cancer Hospital (CN)
Publication Details
- Journal
- BMC Cancer
- Published
- 2025-01-27
- DOI
- https://doi.org/10.1186/s12885-025-13571-9
- Citations
- 2
- Primary Topic
- Breast Cancer Treatment Studies
- Type
- article
- Field-Weighted Citation Impact
- 1.87
Funders
- Wu Jieping Medical Foundation
- Sichuan Province Science and Technology Support Program