Metatranscriptomic time series insight into antibiotic resistance genes and mobile genetic elements in wastewater systems under antibiotic selective pressure
The P14171 gene was the only key ARG that responded to ampicillin degradation in the tested activated sludge systems, indicating its ability and potential health risk. External ampicillin could accelerate HGT in activated sludge systems by increasing the transcription of MGEs.
Authors
- Yuanfang Chen
- Ming Xu (ORCID: https://orcid.org/0000-0001-8846-2880)
- Li Ye (ORCID: https://orcid.org/0000-0001-7688-4867)
- Lei Han (ORCID: https://orcid.org/0000-0002-0707-5027)
- Andong Li (ORCID: https://orcid.org/0000-0001-5291-2720)
- Baoli Zhu (ORCID: https://orcid.org/0000-0001-5326-9503)
Institutions
- Nanjing Health and Health Commission (CN)
- Jiangsu Provincial Center for Disease Control and Prevention (CN)
- Nanjing Medical University (CN)
Publication Details
- Journal
- BMC Microbiology
- Published
- 2025-01-27
- DOI
- https://doi.org/10.1186/s12866-025-03753-7
- Citations
- 5
- Primary Topic
- Pharmaceutical and Antibiotic Environmental Impacts
- Type
- article
- Field-Weighted Citation Impact
- 2.52
Funders
- University of Hong Kong
- Nanjing Medical University