Micrometer-sized liposomes self-aggregate by forming DNA duplexes on their surfaces more sensitively than metallic nanoparticles

Abstract We demonstrate that liposomes with diameters of more than 10 µm (giant unilamellar vesicles) self-aggregate in a noncrosslinking manner by forming DNA duplexes with blunt ends on their surfaces much more sensitively than gold nanoparticles by virtue of their unique features.