Bile cast nephropathy (cholemic nephropathy) associated with hepatitis A-induced acute liver failure and haemolysis in a patient with glucose-6-phosphate dehydrogenase deficiency
Bile cast nephropathy is a significant yet underrecognised cause of acute kidney injury, often associated with severe hyperbilirubinemia in the setting of acute liver failure.In this case, glucose-6-phosphate dehydrogenase (G6PD) deficiency combined with hepatitis A-induced haemolysis led to elevated bilirubin levels, contributing to kidney injury.This case highlights the importance of extracorporeal therapies in managing bile cast nephropathy and promoting renal function recovery, particularly in the absence of standard treatment guidelines.
Authors
- Karam Karam (ORCID: https://orcid.org/0000-0002-3499-6104)
- Pierre Hani
- Ali Hamdan (ORCID: https://orcid.org/0009-0009-2951-210X)
- Johny Salem (ORCID: https://orcid.org/0000-0003-3693-5089)
- Maria Ziadeh
Institutions
- University of Balamand (LB)
Publication Details
- Journal
- European Journal of Case Reports in Internal Medicine
- Published
- 2025-01-27
- DOI
- https://doi.org/10.12890/2025_005064
- Primary Topic
- Neonatal Health and Biochemistry
- Type
- article
- Field-Weighted Citation Impact
- 0.00