Distinct Ocular Surface Microbiome in Keratoconus Patients Correlate With Local Immune Dysregulation
We discovered a unique microbiome signature of KC which correlated to disease grades and secreted molecular factors and immune cells. Therefore, the altered microbiome on the ocular surface may drive immune dysregulation in KC and provide scope for potential interventions in the future.
Authors
- Tanuja Vaidya
- N. Rajiv Kumar
- Archana Padmanabhan
- Swaminathan Sethu (ORCID: https://orcid.org/0000-0001-9210-2554)
- Ramaraj Kannan (ORCID: https://orcid.org/0009-0005-9334-8747)
- Arkasubhra Ghosh (ORCID: https://orcid.org/0000-0002-6570-5891)
- Sharon D’Souza (ORCID: https://orcid.org/0000-0003-4584-2343)
- Rohit Shetty
- Pooja Khamar
Institutions
- Narayana Nethralaya (IN)
Publication Details
- Journal
- Investigative Ophthalmology & Visual Science
- Published
- 2025-01-27
- DOI
- https://doi.org/10.1167/iovs.66.1.60
- Citations
- 5
- Primary Topic
- Corneal surgery and disorders
- Type
- article
- Field-Weighted Citation Impact
- 6.80