IgG-Mediated Food Intolerance in a Patient with Allergic Symptoms, Acne and Obesity - Effect of Elimination Diet

BACKGROUND: Although the association of food-specific IgG with the development and progression of specific diseases has been shown by many studies, strong correlations are still under question. Are these antibodies a normal immune response to foods, or is the pathogenetic mechanism triggered in another way? Why do elimination diets improve, in many studies, different diseases at different ages? CASE PRESENTATION: We will present the case of a patient who experienced significant improvement in allergic symptoms and reduced body weight by implementing an elimination diet. Type III hypersensitivity reactions are associated with IgG antibodies. They are considered to be normal reactions to food antigens. They are absorbed into the bloodstream in small amounts. However, immediately after a meal, antibodies and food antigen complexes bound to specific IgG circulate in the serum, rapidly cleared by a healthy immune system, specifically the reticuloendothelial system. If large amounts of antibodies are produced and immune complexes are deposited in the blood vessels of various organs and organ systems, various manifestations may occur. CONCLUSION: This is a new field of medicine. Further research, better-standardized tests, and much more extensive studies are needed to prove how to utilize the IgG antibody-based elimination diet properly.