Col5a3 Likely Promotes Adipogenesis of 3T3-L1 Through Oxidative Phosphorylation
This study demonstrates the regulatory role of <i>Col5a3</i> in the proliferation and differentiation of preadipocytes, identifying various genes regulated by <i>Col5a3</i> in adipogenesis. We speculate that <i>Col5a3</i> may influence adipogenesis through the oxidative phosphorylation pathway in 3T3-L1 cells. The findings help gain a better understanding of the molecular mechanisms underlying fat deposition and obesity-related metabolic diseases.
Authors
- Yuebo Zhang
- Ruimin Ren
- Hang Yuan (ORCID: https://orcid.org/0009-0004-1897-1718)
- Sheng Wen (ORCID: https://orcid.org/0000-0002-0700-1730)
- Jun He (ORCID: https://orcid.org/0000-0002-1963-9766)
- Ning Gao (ORCID: https://orcid.org/0000-0001-9216-2725)
Institutions
- Ministry of Agriculture and Rural Affairs (CN)
- Hunan Agricultural University (CN)
Publication Details
- Journal
- Genes
- Published
- 2025-01-27
- DOI
- https://doi.org/10.3390/genes16020165
- Primary Topic
- Adipokines, Inflammation, and Metabolic Diseases
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- National Natural Science Foundation of China
- Natural Science Foundation of Hunan Province