Optimizing Convolutional Neural Network Architectures with Optimal Activation Functions for Pediatric Pneumonia Diagnosis Using Chest X-Rays

Pneumonia remains a significant cause of morbidity and mortality among pediatric patients worldwide. Accurate and timely diagnosis is crucial for effective treatment and improved patient outcomes. Traditionally, pneumonia diagnosis has relied on a combination of clinical evaluation and radiologists’ interpretation of chest X-rays. However, this process is time-consuming and prone to inconsistencies in diagnosis. The integration of advanced technologies such as Convolutional Neural Networks (CNNs) into medical diagnostics offers a potential to enhance the accuracy and efficiency. In this study, we conduct a comprehensive evaluation of various activation functions within CNNs for pediatric pneumonia classification using a dataset of 5856 chest X-ray images. The novel Mish activation function was compared with Swish and ReLU, demonstrating superior performance in terms of accuracy, precision, recall, and F1-score in all cases. Notably, InceptionResNetV2 combined with Mish activation function achieved the highest overall performance with an accuracy of 97.61%. Although the dataset used may not fully represent the diversity of real-world clinical cases, this research provides valuable insights into the influence of activation functions on CNN performance in medical image analysis, laying a foundation for future automated pneumonia diagnostic systems.