M6a demethylase FTO regulates the oxidative stress, mitochondrial biogenesis of cardiomyocytes and PGC-1a stability in myocardial ischemia-reperfusion injury
Our study revealed the role of FTO regulates the oxidative stress and mitochondrial biogenesis via PGC-1a in MIRI, which may provide a new approach to mitigating MIRI.
Authors
- Kezeng Gong
- Xuehai Chen
- Feilong Zhang
- Zhe Xu (ORCID: https://orcid.org/0000-0002-9705-8924)
- Lianglong Chen (ORCID: https://orcid.org/0000-0002-5551-6210)
- Qiong Jiang (ORCID: https://orcid.org/0000-0003-1936-9302)
Institutions
- Fujian Medical University (CN)
- Fujian Institute of Microbiology (CN)
- Union Hospital (CN)
Publication Details
- Journal
- Redox Report
- Published
- 2025-01-27
- DOI
- https://doi.org/10.1080/13510002.2025.2454892
- Citations
- 11
- Primary Topic
- Cardiac Structural Anomalies and Repair
- Type
- article
- Field-Weighted Citation Impact
- 22.07
Funders
- National Natural Science Foundation of China
- Natural Science Foundation of Fujian Province
- Fujian Provincial Health Technology Project