Synthesis of Quinine Ester of Naproxen and Study of Its Photophysical Properties
Quinine Ester of Naproxen was obtained for the first time by O-acylation of quinine with naproxen [(S)-6-methoxy-α-methyl-2-naphthaleneacetic acid] chloride under alkaline conditions. The structure of the product was proved by 1H NMR. The photophysical properties of the resulting compound were studied, an intense fluorescent response to picric acid with a Stern–Volmer constant Ksv ≈ 1×106 M–1 was shown.
Authors
- Dmitry S. Kopchuk (ORCID: https://orcid.org/0000-0002-0397-4033)
- Igor S. Коvalev (ORCID: https://orcid.org/0000-0002-0537-3274)
- G. V. Zyryanov
- Ilya N. Egorov (ORCID: https://orcid.org/0000-0003-1402-2684)
- Мaria I. Valieva (ORCID: https://orcid.org/0000-0001-5965-1527)
Institutions
- Ural Federal University (RU)
- Institute of Organic Synthesis (RU)
- Ural Branch of the Russian Academy of Sciences (RU)
Publication Details
- Journal
- Russian Journal of General Chemistry
- Published
- 2024-12-01
- DOI
- https://doi.org/10.1134/s1070363224120156
- Primary Topic
- Free Radicals and Antioxidants
- Type
- article
- Field-Weighted Citation Impact
- 0.00