Estrogen Receptors and Platelet-Activating Acetylhydrolase Activity in the Pathogenesis of Systemic Lupus Erythematosus

The activation of ER<sub>α</sub> and inactivation of ER<sub>β</sub> can cause inflammatory and cutaneous symptoms of SLE, respectively, implying that ER<sub>α</sub> antagonists and/or ER<sub>β</sub> agonists can be useful for the prevention and treatment of SLE.

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Publication Details

Journal
Pharmacology
Published
2025-01-27
DOI
https://doi.org/10.1159/000543797
Citations
1
Primary Topic
Systemic Lupus Erythematosus Research
Type
article
Field-Weighted Citation Impact
1.67
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article

Estrogen Receptors and Platelet-Activating Acetylhydrolase Activity in the Pathogenesis of Systemic Lupus Erythematosus

Akira Sato, Makoto Ohira, Genta Sato, Yasuhiro Ogawa et al.
1 citations
Pharmacology
Systemic Lupus Erythematosus Research
1.67
article

Estrogen Receptors and Platelet-Activating Acetylhydrolase Activity in the Pathogenesis of Systemic Lupus Erythematosus

Akira Sato, Makoto Ohira, Genta Sato, Yasuhiro Ogawa, Hina Nemoto, Akira Yabuki
article en
1 citations

Abstract

The activation of ER<sub>α</sub> and inactivation of ER<sub>β</sub> can cause inflammatory and cutaneous symptoms of SLE, respectively, implying that ER<sub>α</sub> antagonists and/or ER<sub>β</sub> agonists can be useful for the prevention and treatment of SLE.

PharmacologyVol. 110(4)
Miyagi Gakuin Women's University (JP), IRYO Sosei University (JP)
Good health and well-being
Openalex Percentile: Top 21%
Systemic Lupus Erythematosus Research
1.67
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