Synthesis and Antioxidant Activity of N-Substituted Diamides Based on Ethyl N-(2-Allyl-2-arylpent-4-en-1-yl)oxamate

The reactions of 2-allyl-2-arylpent-4-en-1-amines with diethyl oxalate were used to synthesize ethyl oxamates, which were further reacted with nonaromatic amines to obtain the corresponding diamides. To synthesize aryl-substituted oxamides, the same amines are reacted with ethyl N-aryloxamates. The antioxidant activity of the synthesized diamides was studied.

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Publication Details

Journal
Russian Journal of Organic Chemistry
Published
2024-11-01
DOI
https://doi.org/10.1134/s1070428024110046
Primary Topic
Synthesis and biological activity
Type
article
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article

Synthesis and Antioxidant Activity of N-Substituted Diamides Based on Ethyl N-(2-Allyl-2-arylpent-4-en-1-yl)oxamate

H. А. Panosyan, G. G. Mkryan, H. B. Sargsyan, А. А. Aghekyan et al.
Russian Journal of Organic Chemistry
Synthesis and biological activity
article

Synthesis and Antioxidant Activity of N-Substituted Diamides Based on Ethyl N-(2-Allyl-2-arylpent-4-en-1-yl)oxamate

H. А. Panosyan, G. G. Mkryan, H. B. Sargsyan, А. А. Aghekyan, H. V. Gasparyan, G. V. Stepanyan, H. A. Pahutyan
article en

Abstract

The reactions of 2-allyl-2-arylpent-4-en-1-amines with diethyl oxalate were used to synthesize ethyl oxamates, which were further reacted with nonaromatic amines to obtain the corresponding diamides. To synthesize aryl-substituted oxamides, the same amines are reacted with ethyl N-aryloxamates. The antioxidant activity of the synthesized diamides was studied.

Russian Journal of Organic ChemistryVol. 60(11)
Institute of Fine Organic Chemistry of Scientific - Technological Center of Organic and Pharmaceutical Chemistry (AM)
Openalex Percentile: Top 81%
Synthesis and biological activity
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Synthesis and Antioxidant Activity of N-Substituted Diamides Based on Ethyl N-(2-Allyl-2-arylpent-4-en-1-yl)oxamate — H. А. Panosyan, G. G. Mkryan, et al. · Russian Journal of Organic Chemistry (2024) | TGRS Research Map | TGRS