Synthesis, Characterization, and Biological Evaluation for New Derivatives Based on 2Сhloro-N-[4-(5-phenyl-1,3,4-oxadiazol-2-yl)phenyl]acetamide

A new compound, 2-chloro-N-[4-(5-phenyl-1,3,4-oxadiazol-2-yl)phenyl]acetamide, was obtained using a multi-step reaction and converted into the corresponding aldehyde. The latter was used for the synthesis of new Schiff bases derivatives. These compounds were characterized via physical and spectral data (IR, 1H NMR) besides to CHN analysis of some of them and biological activity. Such types of activities as enzyme inhibition, antimicrobial and antifungal activity were studied.

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Publication Details

Journal
Russian Journal of General Chemistry
Published
2024-12-01
DOI
https://doi.org/10.1134/s1070363224120259
Citations
2
Primary Topic
Synthesis and biological activity
Type
article
Field-Weighted Citation Impact
0.50
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article

Synthesis, Characterization, and Biological Evaluation for New Derivatives Based on 2Сhloro-N-[4-(5-phenyl-1,3,4-oxadiazol-2-yl)phenyl]acetamide

H. Hassan, Hoda S. Ahmed, K. A. Alheety, Nebras M. Jamel et al.
2 citations
Russian Journal of General Chemistry
Synthesis and biological activity
0.50
article

Synthesis, Characterization, and Biological Evaluation for New Derivatives Based on 2Сhloro-N-[4-(5-phenyl-1,3,4-oxadiazol-2-yl)phenyl]acetamide

H. Hassan, Hoda S. Ahmed, K. A. Alheety, Nebras M. Jamel, R. K. Baqir, Jumbad H. Tomma
article en
2 citations

Abstract

A new compound, 2-chloro-N-[4-(5-phenyl-1,3,4-oxadiazol-2-yl)phenyl]acetamide, was obtained using a multi-step reaction and converted into the corresponding aldehyde. The latter was used for the synthesis of new Schiff bases derivatives. These compounds were characterized via physical and spectral data (IR, 1H NMR) besides to CHN analysis of some of them and biological activity. Such types of activities as enzyme inhibition, antimicrobial and antifungal activity were studied.

Russian Journal of General ChemistryVol. 94(12)
University of Baghdad (IQ)
Openalex Percentile: Top 37%
Synthesis and biological activity
0.50
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