6-Nitroazolo[1,5-a]pyrimidines and 6-Nitroazolo[5,1-c][1,2,4]triazines in the Nucleophilic Sulfation Reaction
A method has been developed for the introduction of a sulfo group into molecules of 6-nitro derivatives of azoloanneled [1,5-a]pyrimidines and [5,1-c][1,2,4]triazines via a nucleophilic addition reaction (AN). The antimicrobial activity of some synthesized compounds was evaluated with respect to the control strain of Neisseria gonorrhoeae ATCC 49226/NCTC 12700 and museum strains of dermatophyte fungi and yeast-like fungi.
Authors
- Н. А. Герасимова (ORCID: https://orcid.org/0000-0001-5370-5571)
- Павел А. Слепухин (ORCID: https://orcid.org/0000-0001-8132-9905)
- Gennady L. Rusinov (ORCID: https://orcid.org/0000-0001-8567-9435)
- Evgeny B. Gorbunov (ORCID: https://orcid.org/0000-0003-0740-3358)
- I.G. Ovchinnikova (ORCID: https://orcid.org/0000-0002-3304-6553)
Institutions
- Ural Federal University (RU)
- Ural Scientific Research Institute of Dermatovenerology and Immunopathology (RU)
- Institute of Organic Synthesis (RU)
- Ural Branch of the Russian Academy of Sciences (RU)
Publication Details
- Journal
- Russian Journal of General Chemistry
- Published
- 2024-12-01
- DOI
- https://doi.org/10.1134/s1070363224120119
- Primary Topic
- Chemical Reaction Mechanisms
- Type
- article
- Field-Weighted Citation Impact
- 0.00