Green Manufacture of Hydrated Polymers Coatings with On-Demand Mechanics and Lubricity Based on Novel Biobased Polymerizable Deep Eutectic Solvents

The aging population necessitates a critical need for medical devices, where polymers-based surface lubrication coating is essential for optimal functionality. In fact, lubrication and mechanical requirements vary depending on the service environment of different medical devices. Until now, key mean is still blank for general preparation of hydrophilic polymers-based lubrication coatings with on-demand mechanics and lubricity. This study introduces a novel hydrophilic lubrication coating with tunable mechanical properties and lubricity, derived from eco-friendly polymerizable deep eutectic solvents (PDESs) containing betaine, hydroxyethyl acrylate, glycerol, and tannic acid. Unlike traditional high molecular weight polymers, this approach leverages small-molecule, high-biobased PDESs, thereby simplifying the synthesis process. The resulting coating demonstrates exceptional adhesion to a range of medical device materials─including glass, stainless steel, polyvinyl chloride, and polyurethane─thanks to the high content of hydroxyl groups and pyrogallol motifs from tannic acid. It also enables the precise tuning of mechanical strength, modulus, adhesion, hydrophilicity, and lubrication properties by varying the amounts of glycerol and tannic acid. Furthermore, the coating undergoes a hydration-induced transition from high-strength, high-friction to low-strength, low-friction states, maintaining repeatable performance. Additionally, the synergistic effects of betaine and tannic acid in the PDES contribute to its notable antimicrobial properties. In summary, these PDESs demonstrate significant potential for enhancing lubrication in a range of biomedical devices.