Fasting-mimicking diet-enriched <i>Bifidobacterium pseudolongum</i> suppresses colorectal cancer by inducing memory CD8 <sup>+</sup> T cells
<i>B. pseudolongum</i> contributes to the FMD antitumour effects in CRC by producing L-arginine. This promotes CD8<sup>+</sup> T-cell differentiation into memory cells. <i>B. pseudolongum</i> administration is a potential CRC therapeutic strategy.
Authors
- Xingfeng Sun (ORCID: https://orcid.org/0000-0003-3078-5681)
- Baichao Yu (ORCID: https://orcid.org/0000-0003-0827-9395)
- Luman Wang (ORCID: https://orcid.org/0000-0003-0121-349X)
- Yiwei Chu (ORCID: https://orcid.org/0000-0002-5035-1111)
- Miaomiao Guo (ORCID: https://orcid.org/0000-0003-1223-9257)
- Changhong Miao (ORCID: https://orcid.org/0000-0002-2809-6599)
- Ying Fu (ORCID: https://orcid.org/0000-0003-1177-0871)
- Ke Nan (ORCID: https://orcid.org/0000-0002-5691-0295)
- Ziwen Zhong (ORCID: https://orcid.org/0000-0002-4578-174X)
- Zhaoyuan Chen
- Mingjie Zhang (ORCID: https://orcid.org/0000-0001-9404-0190)
- Ying Yue (ORCID: https://orcid.org/0000-0001-7657-6020)
- Han Zhang (ORCID: https://orcid.org/0000-0002-0166-1973)
- Zhiqiang Wang (ORCID: https://orcid.org/0000-0002-5573-455X)
- Ronghua Liu (ORCID: https://orcid.org/0000-0002-4197-3971)
- Yang Shen (ORCID: https://orcid.org/0009-0003-9371-5207)
- Mengdi Qu
- Kameina Zhuma
Institutions
- Shanghai Medical College of Fudan University (CN)
- Sun Yat-sen University (CN)
- Fudan University (CN)
- Zhongshan Hospital (CN)
- The First Affiliated Hospital, Sun Yat-sen University (CN)
- Obstetrics and Gynecology Hospital of Fudan University (CN)
- Shanghai Clinical Research Center (CN)
Publication Details
- Journal
- Gut
- Published
- 2025-01-27
- DOI
- https://doi.org/10.1136/gutjnl-2024-333020
- Citations
- 28
- Primary Topic
- Gut microbiota and health
- Type
- article
- Field-Weighted Citation Impact
- 22.57
Funders
- National Natural Science Foundation of China
- Key Programme
- National Key Research and Development Program of China