The cellular response of lipopolysaccharide-induced inflammation in keratoconus human corneal fibroblasts to RB-PDT: Insights into cytokines, chemokines and related signaling pathways
In LPS-induced inflammation of KC-HCFs treated with RB-PDT, despite the increased expression of pro-inflammatory cytokines, the activation of the TLR4 signaling pathways is lacking. RB-PDT may have no adverse effects on corneal scar formation of keratoconus corneas in the short term.
Authors
- Tanja Stachon (ORCID: https://orcid.org/0000-0001-7009-7125)
- Tim Berger (ORCID: https://orcid.org/0000-0003-2307-2237)
- Zhen Li (ORCID: https://orcid.org/0000-0001-5491-2169)
- Maryam Amini (ORCID: https://orcid.org/0009-0000-3118-9959)
- Shweta Suiwal (ORCID: https://orcid.org/0000-0002-1230-1279)
- Achim Langenbucher (ORCID: https://orcid.org/0000-0001-9175-6177)
- Stefan Hacker (ORCID: https://orcid.org/0000-0002-6376-4687)
- Nóra Szentmáry (ORCID: https://orcid.org/0000-0001-8019-1481)
- Berthold Seitz (ORCID: https://orcid.org/0000-0001-9701-8204)
- Ning Chai (ORCID: https://orcid.org/0000-0001-9689-8887)
Institutions
- Semmelweis University (HU)
- Anhui Medical University (CN)
- First Affiliated Hospital of Anhui Medical University (CN)
- Saarland University (DE)
Publication Details
- Journal
- PLoS ONE
- Published
- 2025-01-27
- DOI
- https://doi.org/10.1371/journal.pone.0318132
- Citations
- 1
- Primary Topic
- Corneal surgery and disorders
- Type
- article
- Field-Weighted Citation Impact
- 1.36