Distinguishing benign and malignant myxoid soft tissue tumors: Performance of radiomics vs. radiologists
A radiomic based ML model predicted benign or malignant diagnosis in myxoid soft tissue tumors similarly to the consensus diagnosis by three musculoskeletal radiologists. Radiologist confidence in the diagnosis strongly correlated with their diagnostic accuracy. Though radiomics and radiologists perform similarly overall, radiomics may provide novel diagnostic utility when radiologist confidence is low, or when radiologists disagree.
Authors
- Benoît M. Dawant (ORCID: https://orcid.org/0000-0002-3804-8400)
- Herbert S. Schwartz (ORCID: https://orcid.org/0000-0001-6591-8179)
- Akhil Rekulapelli (ORCID: https://orcid.org/0000-0002-3350-4366)
- Hakmook Kang (ORCID: https://orcid.org/0000-0001-6876-4021)
- Ginger E. Holt (ORCID: https://orcid.org/0000-0001-5497-9419)
- Jennifer L. Halpern (ORCID: https://orcid.org/0000-0003-4812-2755)
- Leo Y. Luo (ORCID: https://orcid.org/0000-0002-3061-4287)
- Joanna Shechtel (ORCID: https://orcid.org/0009-0005-0218-0476)
- John J. Block (ORCID: https://orcid.org/0000-0002-8480-8765)
- Brian Bingham (ORCID: https://orcid.org/0000-0002-7168-1195)
- Cullen P. Moran (ORCID: https://orcid.org/0000-0003-2337-6118)
- Stephen Chenard (ORCID: https://orcid.org/0000-0003-1029-7015)
- David S. Smith (ORCID: https://orcid.org/0000-0002-1615-2231)
- Samuel Johnson (ORCID: https://orcid.org/0000-0003-4032-2058)
- Nicholson S. Chadwick (ORCID: https://orcid.org/0000-0002-2024-9482)
- Joshua M. Lawrenz (ORCID: https://orcid.org/0000-0003-4069-7044)
- Can Cui (ORCID: https://orcid.org/0009-0009-7082-3444)
- Katherine S. Hajdu
Institutions
- Vanderbilt University Medical Center (US)
Publication Details
- Journal
- PLoS ONE
- Published
- 2025-01-27
- DOI
- https://doi.org/10.1371/journal.pone.0318072
- Primary Topic
- Bone Tumor Diagnosis and Treatments
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- American Cancer Society