Association of P2X7 polymorphisms on Type 2 diabetes mellitus susceptibility and diabetic complications

We found that P2X7 polymorphisms are significantly associated with the risk of T2DM and its complications, suggesting that targeting P2X7 may offer a novel therapeutic strategy for the prevention and personal treatment of T2DM.

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Publication Details

Journal
PLoS ONE
Published
2025-01-27
DOI
https://doi.org/10.1371/journal.pone.0318134
Citations
1
Primary Topic
Adenosine and Purinergic Signaling
Type
article
Field-Weighted Citation Impact
1.12

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article

Association of P2X7 polymorphisms on Type 2 diabetes mellitus susceptibility and diabetic complications

G.-Y. Huang, Qi Chen, Jing Cheng, Qian Zhang et al.
1 citations
PLoS ONE
Adenosine and Purinergic Signaling
1.12
article

Association of P2X7 polymorphisms on Type 2 diabetes mellitus susceptibility and diabetic complications

G.-Y. Huang, Qi Chen, Jing Cheng, Qian Zhang, Tong Yang, Wenfeng Liu, Ye Tao, Yuzhong Xu
article en
1 citations

Abstract

We found that P2X7 polymorphisms are significantly associated with the risk of T2DM and its complications, suggesting that targeting P2X7 may offer a novel therapeutic strategy for the prevention and personal treatment of T2DM.

PLoS ONEVol. 20(1)
Shenzhen Bao'an District People's Hospital (CN), State Key Laboratory of Respiratory Disease (CN), Guangzhou Medical University (CN)
Basic and Applied Basic Research Foundation of Guangdong Province
Good health and well-being
Openalex Percentile: Top 29%
Adenosine and Purinergic Signaling
1.12
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Association of P2X7 polymorphisms on Type 2 diabetes mellitus susceptibility and diabetic complications — G.-Y. Huang, Qi Chen, et al. · PLoS ONE (2025) | TGRS Research Map | TGRS