Intestinal atresia: a retrospective study of 36 neonates and risk factors to mortality in Tertiary care center, Tripura

Background: Intestinal atresia among neonates is still a condition which has huge morbidity and mortality, particularly in the developing world. We share a case series of intestinal atresia in context of their presentation, management and outcome. Methods: This study was conducted at Tripura Medical College and DR BRAM Teaching hospital, Tripura, over 1 year. We included all patients presenting with jejunoileal atresia, duodenal atresia and their demographic details, presentation, investigations, treatment strategies and the outcome were noted at a pre-designed proforma. All data were analysed using SPSS version 26. Results: A total of 36 neonates with intestinal atresia were included. Most of them (77.78%) presented after 48 h of life and the mean age at presentation was 5.68±4.75 days. There were 22 male patients (61.11%) and 30 (83.33%) were full-term. The most common presenting complaint was not being able to pass meconium (88.89%). Type III atresia was the most common subtype (41.67%). Most of them underwent resection without tapering. The mean hospital stay was 12.81±6.53 and it was significantly longer among those who underwent re-exploration (P=0.034). 13 patients (36.11%) expired within 6 months of follow-up. The only significant factor for mortality was the presence of short bowel syndrome (P=0.036). All other demographic and management factors did not alter the mortality rate. Conclusions: Management of surgical neonates is a difficult job in developing countries with limited resources. There is a high mortality rate of neonates following intestinal atresia surgeries and surgeons in these countries must fight on many fronts to improve the outcome.

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Publication Details

Journal
International Journal of Contemporary Pediatrics
Published
2025-01-27
DOI
https://doi.org/10.18203/2349-3291.ijcp20250087
Primary Topic
Intestinal Malrotation and Obstruction Disorders
Type
article
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article

Intestinal atresia: a retrospective study of 36 neonates and risk factors to mortality in Tertiary care center, Tripura

Abheek Sil, Manidipa Sarkar, Aniruddha Basak
International Journal of Contemporary Pediatrics
Intestinal Malrotation and Obstruction Disorders
article

Intestinal atresia: a retrospective study of 36 neonates and risk factors to mortality in Tertiary care center, Tripura

Abheek Sil, Manidipa Sarkar, Aniruddha Basak
article en

Abstract

Background: Intestinal atresia among neonates is still a condition which has huge morbidity and mortality, particularly in the developing world. We share a case series of intestinal atresia in context of their presentation, management and outcome. Methods: This study was conducted at Tripura Medical College and DR BRAM Teaching hospital, Tripura, over 1 year. We included all patients presenting with jejunoileal atresia, duodenal atresia and their demographic details, presentation, investigations, treatment strategies and the outcome were noted at a pre-designed proforma. All data were analysed using SPSS version 26. Results: A total of 36 neonates with intestinal atresia were included. Most of them (77.78%) presented after 48 h of life and the mean age at presentation was 5.68±4.75 days. There were 22 male patients (61.11%) and 30 (83.33%) were full-term. The most common presenting complaint was not being able to pass meconium (88.89%). Type III atresia was the most common subtype (41.67%). Most of them underwent resection without tapering. The mean hospital stay was 12.81±6.53 and it was significantly longer among those who underwent re-exploration (P=0.034). 13 patients (36.11%) expired within 6 months of follow-up. The only significant factor for mortality was the presence of short bowel syndrome (P=0.036). All other demographic and management factors did not alter the mortality rate. Conclusions: Management of surgical neonates is a difficult job in developing countries with limited resources. There is a high mortality rate of neonates following intestinal atresia surgeries and surgeons in these countries must fight on many fronts to improve the outcome.

International Journal of Contemporary PediatricsVol. 12(2)
Tripura Medical College & Dr. B.R. Ambedkar Memorial Teaching Hospital (IN)
Openalex Percentile: Top 97%
Intestinal Malrotation and Obstruction Disorders
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Intestinal atresia: a retrospective study of 36 neonates and risk factors to mortality in Tertiary care center, Tripura — Abheek Sil, Manidipa Sarkar, et al. · International Journal of Contemporary Pediatrics (2025) | TGRS Research Map | TGRS