Safety of interleukin inhibitors in patients with plaque psoriasis and history of neoplasms: a multicenter retrospective study – IL PSO (Italian landscape psoriasis)
<b>Results:</b> Three patients experienced neoplasm recurrence during treatment with IL inhibitors, which led to the discontinuation of these drugs. In our study, biologics have demonstrated safety and effectiveness as treatment options for patients with both a history of neoplasm and those with concurrent tumors. However, further investigation is needed, particularly through larger and longer multicenter studies.
Authors
- Simone Ribero (ORCID: https://orcid.org/0000-0002-0098-1406)
- Francesco Loconsole (ORCID: https://orcid.org/0000-0003-2852-9451)
- Angelo Valerio Marzano (ORCID: https://orcid.org/0000-0002-2258-8357)
- Luigi Gargiulo (ORCID: https://orcid.org/0000-0002-6051-1676)
- Eugenia Veronica Di Brizzi (ORCID: https://orcid.org/0000-0002-0278-2443)
- Matteo Megna (ORCID: https://orcid.org/0000-0003-1803-2046)
- Piergiorgio Malagoli (ORCID: https://orcid.org/0000-0002-6181-6922)
- Paolo Dapavo
- Valentina Dini (ORCID: https://orcid.org/0000-0002-8537-1999)
- Antonio Costanzo (ORCID: https://orcid.org/0000-0001-9697-2557)
- Anna Balato (ORCID: https://orcid.org/0000-0001-5485-0172)
- Luca Potestio (ORCID: https://orcid.org/0000-0001-5940-0592)
- Mario Valenti (ORCID: https://orcid.org/0000-0001-9140-9263)
- Alessandra Michelucci (ORCID: https://orcid.org/0000-0002-0795-0338)
- Luciano Ibba (ORCID: https://orcid.org/0000-0002-7876-4866)
- Alessandra Narcisi (ORCID: https://orcid.org/0000-0002-1938-8581)
- Francesca Maria Gaiani (ORCID: https://orcid.org/0009-0003-7613-4451)
- S. Di Giulio (ORCID: https://orcid.org/0009-0001-3780-5318)
- Carlo Giovanni Carrera
Institutions
- Humanitas University (IT)
- University of Milan (IT)
- University of Campania "Luigi Vanvitelli" (IT)
- Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico (IT)
- Ospedale Santa Chiara (IT)
- IRCCS Policlinico San Donato (IT)
- University of Campania "Luigi Vanvitelli" (IT)
- University Dermatology (US)
- Ospedale San Donato (IT)
- IRCCS Humanitas Research Hospital (IT)
- University of Turin (IT)
- University of Bari Aldo Moro (IT)
- University of Naples Federico II (IT)
Publication Details
- Journal
- Journal of Dermatological Treatment
- Published
- 2025-01-27
- DOI
- https://doi.org/10.1080/09546634.2025.2456532
- Citations
- 4
- Primary Topic
- Psoriasis: Treatment and Pathogenesis
- Type
- article
- Field-Weighted Citation Impact
- 3.19