Combined intrathecal baclofen pump revision to the cervical level and lumbosacral ventral-dorsal rhizotomy for severe medically refractory hypertonia: illustrative cases

The authors highlight favorable outcomes using multimodal surgery in pediatric patients. Multimodal therapy is surgically feasible and better addresses MRH, particularly in patients in whom ITB monotherapy and polypharmacy have failed. Future studies with larger patient volumes are necessary to optimize indications and make more definitive outcome conclusions. https://thejns.org/doi/10.3171/CASE24599.

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Publication Details

Journal
Journal of Neurosurgery Case Lessons
Published
2025-01-27
DOI
https://doi.org/10.3171/case24599
Primary Topic
Botulinum Toxin and Related Neurological Disorders
Type
article
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article

Combined intrathecal baclofen pump revision to the cervical level and lumbosacral ventral-dorsal rhizotomy for severe medically refractory hypertonia: illustrative cases

James M. Mossner, Jeffrey S. Raskin, Sunny Abdelmageed, Benjamin Katholi et al.
Journal of Neurosurgery Case Lessons
Botulinum Toxin and Related Neurological Disorders
article

Combined intrathecal baclofen pump revision to the cervical level and lumbosacral ventral-dorsal rhizotomy for severe medically refractory hypertonia: illustrative cases

James M. Mossner, Jeffrey S. Raskin, Sunny Abdelmageed, Benjamin Katholi, Robin Trierweiler, Mary Keen, Gloria Bae
article en

Abstract

The authors highlight favorable outcomes using multimodal surgery in pediatric patients. Multimodal therapy is surgically feasible and better addresses MRH, particularly in patients in whom ITB monotherapy and polypharmacy have failed. Future studies with larger patient volumes are necessary to optimize indications and make more definitive outcome conclusions. https://thejns.org/doi/10.3171/CASE24599.

Journal of Neurosurgery Case LessonsVol. 9(4)
Northwestern University (US), Marianjoy Rehabilitation Hospital (US), National Audubon Society (US), Lurie Children's Hospital (US), Shirley Ryan AbilityLab (US), Rosalind Franklin University of Medicine and Science (US), Globus Medical (United States) (US)
Good health and well-being
Openalex Percentile: Top 98%
Botulinum Toxin and Related Neurological Disorders
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Combined intrathecal baclofen pump revision to the cervical level and lumbosacral ventral-dorsal rhizotomy for severe medically refractory hypertonia: illustrative cases — James M. Mossner, Jeffrey S. Raskin, et al. · Journal of Neurosurgery Case Lessons (2025) | TGRS Research Map | TGRS