Ginsenoside Rg5 alleviates radiation-induced acute lung vascular endothelium injury by reducing mitochondrial apoptosis via Sirt1
Ginsenoside Rg5 exerts a protective effect against radiation-induced endothelial injury by modulating mitochondrial dynamics and function, as well as maintaining endothelial barrier integrity, in a Sirt1-dependent manner.
Authors
- Hao Kuang
- Tao Li (ORCID: https://orcid.org/0000-0002-7246-2613)
- Jing Xiong (ORCID: https://orcid.org/0000-0002-9712-6771)
- Churong Li (ORCID: https://orcid.org/0000-0002-4361-1704)
- Hansong Bai (ORCID: https://orcid.org/0000-0002-3965-738X)
- Linjie Li (ORCID: https://orcid.org/0000-0003-4180-4614)
- Long Chen (ORCID: https://orcid.org/0000-0002-7347-3074)
- Long Liang (ORCID: https://orcid.org/0000-0002-2538-6726)
- Jiahua Lyu
- Mira Jung
- Keith Unger
- Dalong Pang
- Biao Zhao
Institutions
- University of Electronic Science and Technology of China (CN)
- Georgetown University (US)
- Chengdu Medical College (CN)
- Georgetown University Medical Center (US)
- Affiliated Hospital of Southwest Medical University (CN)
- Sichuan Cancer Hospital (CN)
Publication Details
- Journal
- Journal of Ginseng Research
- Published
- 2025-01-27
- DOI
- https://doi.org/10.1016/j.jgr.2025.01.004
- Citations
- 5
- Primary Topic
- Ginseng Biological Effects and Applications
- Type
- article
- Field-Weighted Citation Impact
- 4.03
Funders
- Natural Science Foundation of Sichuan Province