An Operationally Simple, Regioselective, Platinum‐Catalyzed Hydroboration of Unactivated Alkynes
Abstract Herein is reported a new PtCl 2 /XPhos/Et 3 SiH‐catalyzed hydroboration method for unactivated terminal alkynes. Significantly, the reaction proceeds in hindered alkyne systems, and works well on acetylenes that contain multiple heteroatom‐groups to provide the desired ( E )‐1,2‐vinyl boronates in reasonable to high yields with excellent levels of stereo‐ and regio‐control.
Authors
- Karl J. Hale (ORCID: https://orcid.org/0000-0002-6756-8763)
- Mark McLaughlin (ORCID: https://orcid.org/0000-0002-5999-4703)
- Dean D. Roberts (ORCID: https://orcid.org/0009-0009-2836-0546)
Institutions
- Queen's University Belfast (GB)
- Stranmillis University College (GB)
- Lancaster University (GB)
Publication Details
- Journal
- European Journal of Organic Chemistry
- Published
- 2025-01-27
- DOI
- https://doi.org/10.1002/ejoc.202401355
- Citations
- 6
- Primary Topic
- Organoboron and organosilicon chemistry
- Type
- article
- Field-Weighted Citation Impact
- 5.62
Funders
- Queen's University Belfast
- Queen's University