The U-shaped association of fasting plasma glucose to HbA1c ratio with mortality in diabetic and prediabetic populations: the mediating role of systemic immune-inflammation index
In the prospective cohort, the FPG/HbA1c ratio demonstrated a U-shaped association with mortality in diabetic and prediabetic adults, with SII playing a significant mediating role. These findings suggest that interventions targeting immunity and inflammation may improve clinical outcomes in these populations.
Authors
- Ming Yang (ORCID: https://orcid.org/0000-0002-4895-5864)
- Guotai Sheng (ORCID: https://orcid.org/0000-0001-5298-4724)
- Jingqi Yang (ORCID: https://orcid.org/0000-0002-8053-5616)
- Qing Shangguan
- Guobo Xie
Institutions
- First Affiliated Hospital of Jiangxi Medical College (CN)
- Jiangxi Provincial People's Hospital (CN)
Publication Details
- Journal
- Frontiers in Endocrinology
- Published
- 2025-01-27
- DOI
- https://doi.org/10.3389/fendo.2025.1465242
- Primary Topic
- Hyperglycemia and glycemic control in critically ill and hospitalized patients
- Type
- article
- Field-Weighted Citation Impact
- 0.00