Adoption of Electrochemistry within the Pharmaceutical Industry: Insights from an Industry-Wide Survey

This article presents the results of a comprehensive survey on the adoption of electrochemistry among 17 major pharmaceutical companies. The study examined key areas, including motivation, vision, personnel, utilization, explored reactions, scale-up experience, and equipment, with a focus on identifying gaps that hinder the realization of electrochemistry’s full potential. The survey findings suggest that although the adoption of electrochemistry is still in its early stages, it is viewed as a promising area that could lead to novel, better, and differentiated chemical transformations and disruptive routes. None of the surveyed companies reported having commercialized electrochemical processes; however, many anticipate reaching late-stage development or commercialization within a few years. The survey provides valuable insights for both industrial and academic laboratories seeking to pursue research in this field. Addressing gaps in knowledge and technology is essential to realizing the potential benefits of electrochemistry, ultimately contributing to the development of more efficient and sustainable manufacturing processes in the pharmaceutical industry.

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Publication Details

Journal
Organic Process Research & Development
Published
2025-01-27
DOI
https://doi.org/10.1021/acs.oprd.4c00353
Citations
10
Primary Topic
Innovative Microfluidic and Catalytic Techniques Innovation
Type
article
Field-Weighted Citation Impact
6.74
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article

Adoption of Electrochemistry within the Pharmaceutical Industry: Insights from an Industry-Wide Survey

Michael O. Frederick, Dan Lehnherr, Benjamin M. Cohen, Lin Deng et al.
10 citations
Organic Process Research & Development
Innovative Microfluidic and Catalytic Techniques Innovation
6.74
article

Adoption of Electrochemistry within the Pharmaceutical Industry: Insights from an Industry-Wide Survey

Michael O. Frederick, Dan Lehnherr, Benjamin M. Cohen, Lin Deng, Moiz Diwan, Antonio C. Ferretti
article en
10 citations

Abstract

This article presents the results of a comprehensive survey on the adoption of electrochemistry among 17 major pharmaceutical companies. The study examined key areas, including motivation, vision, personnel, utilization, explored reactions, scale-up experience, and equipment, with a focus on identifying gaps that hinder the realization of electrochemistry’s full potential. The survey findings suggest that although the adoption of electrochemistry is still in its early stages, it is viewed as a promising area that could lead to novel, better, and differentiated chemical transformations and disruptive routes. None of the surveyed companies reported having commercialized electrochemical processes; however, many anticipate reaching late-stage development or commercialization within a few years. The survey provides valuable insights for both industrial and academic laboratories seeking to pursue research in this field. Addressing gaps in knowledge and technology is essential to realizing the potential benefits of electrochemistry, ultimately contributing to the development of more efficient and sustainable manufacturing processes in the pharmaceutical industry.

Organic Process Research & DevelopmentVol. 29(2)
Merck & Co., Inc., Rahway, NJ, USA (United States) (US), Eli Lilly (United States) (US), AbbVie (United States) (US), Bristol-Myers Squibb (United States) (US), Université Bourgogne Franche-Comté (FR), Alexion Pharmaceuticals (United States) (US), Process Research Ortech (Canada) (CA)
Industry, innovation and infrastructure
Openalex Percentile: Top 3%
Innovative Microfluidic and Catalytic Techniques Innovation
6.74
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Adoption of Electrochemistry within the Pharmaceutical Industry: Insights from an Industry-Wide Survey — Michael O. Frederick, Dan Lehnherr, et al. · Organic Process Research & Development (2025) | TGRS Research Map | TGRS