Adoption of Electrochemistry within the Pharmaceutical Industry: Insights from an Industry-Wide Survey
This article presents the results of a comprehensive survey on the adoption of electrochemistry among 17 major pharmaceutical companies. The study examined key areas, including motivation, vision, personnel, utilization, explored reactions, scale-up experience, and equipment, with a focus on identifying gaps that hinder the realization of electrochemistry’s full potential. The survey findings suggest that although the adoption of electrochemistry is still in its early stages, it is viewed as a promising area that could lead to novel, better, and differentiated chemical transformations and disruptive routes. None of the surveyed companies reported having commercialized electrochemical processes; however, many anticipate reaching late-stage development or commercialization within a few years. The survey provides valuable insights for both industrial and academic laboratories seeking to pursue research in this field. Addressing gaps in knowledge and technology is essential to realizing the potential benefits of electrochemistry, ultimately contributing to the development of more efficient and sustainable manufacturing processes in the pharmaceutical industry.
Authors
- Michael O. Frederick (ORCID: https://orcid.org/0000-0001-5897-3540)
- Dan Lehnherr (ORCID: https://orcid.org/0000-0001-8392-1208)
- Benjamin M. Cohen (ORCID: https://orcid.org/0000-0002-7000-9292)
- Lin Deng (ORCID: https://orcid.org/0000-0002-0132-1901)
- Moiz Diwan (ORCID: https://orcid.org/0000-0001-9019-5291)
- Antonio C. Ferretti (ORCID: https://orcid.org/0000-0002-2475-497X)
Institutions
- Merck & Co., Inc., Rahway, NJ, USA (United States) (US)
- Eli Lilly (United States) (US)
- AbbVie (United States) (US)
- Bristol-Myers Squibb (United States) (US)
- Université Bourgogne Franche-Comté (FR)
- Alexion Pharmaceuticals (United States) (US)
- Process Research Ortech (Canada) (CA)
Publication Details
- Journal
- Organic Process Research & Development
- Published
- 2025-01-27
- DOI
- https://doi.org/10.1021/acs.oprd.4c00353
- Citations
- 10
- Primary Topic
- Innovative Microfluidic and Catalytic Techniques Innovation
- Type
- article
- Field-Weighted Citation Impact
- 6.74