Noninvasive prenatal diagnosis (NIPD) of non-syndromic hearing loss (NSHL) for singleton and twin pregnancies in the first trimester
This study represents the pioneering evidence in the field, demonstrating the feasibility of NIPD for NSHL in twin pregnancies. Moreover, it provides a novel and advanced diagnostic approach for families at high risk of NSHL during pregnancy, offering earlier detection, enhanced safety, and improved accuracy.
Authors
- Zhenhua Zhao (ORCID: https://orcid.org/0000-0001-8952-8677)
- Lingrong Kong (ORCID: https://orcid.org/0000-0001-6432-1100)
- Xiangdong Kong (ORCID: https://orcid.org/0000-0003-4322-914X)
- Jun Feng (ORCID: https://orcid.org/0000-0002-2417-0114)
- Huanyun Li
- Di Wu (ORCID: https://orcid.org/0000-0002-5895-2237)
- Jingqi Zhu (ORCID: https://orcid.org/0009-0008-8268-3365)
- Shaojun Li (ORCID: https://orcid.org/0000-0002-3547-915X)
- Xinyu Fu
- Weiqin Tang
Institutions
- Celula (United States) (US)
- Shanghai First Maternity and Infant Hospital (CN)
- First Affiliated Hospital of Zhengzhou University (CN)
Publication Details
- Journal
- Orphanet Journal of Rare Diseases
- Published
- 2025-01-27
- DOI
- https://doi.org/10.1186/s13023-025-03558-x
- Primary Topic
- Hearing, Cochlea, Tinnitus, Genetics
- Type
- article
- Field-Weighted Citation Impact
- 0.00