Guidelines on Application of Artificial Liver Blood Purification System (Version 2023)

Abstract The artificial liver blood purification system (ALBPS), referred to as the artificial liver system, has been extensively used for treatment of patients with liver failure or other organ failures, and its efficacy has been well-documented. To further standardize the clinical application of ALBPS, the Liver Failure and Artificial Liver Group, Chinese Society of Infectious Diseases, Chinese Medical Association and other institutions invited experts to update the 2016 version of ALBPS guidelines and develop the Guidelines on Application of Artificial Liver Blood Purification System (version 2023) . In line with the latest international research advancements, this updated version comprehensively elaborates on various aspects of ALBPS, including treatment mode selection, anticoagulation program implementation, nursing and operational procedures, indications and relative contraindications, common complications and their management, as well as management regulations of the system. These guidelines will provide guidance for the effective application of ALBPS for treatment of critically ill patients.