Zn-doped CaP coating equips Ti implants with corrosion resistance, biomineralization, antibacterial and immunotolerant activities
Zn-doped CaP coatings on Ti64 implants significantly improved corrosion resistance, bioactivity, and antibacterial performance. We developed an advanced multifunctional biomaterial equipped with beneficial anti-inflammatory and tissue integrative programming of innate immunity providing principal advantages for the long-term implant integration and reducing the implant failure risks.
Authors
- Anca Constantina Pârău (ORCID: https://orcid.org/0000-0002-4661-8362)
- Julia Kzhyshkowska (ORCID: https://orcid.org/0000-0003-0898-3075)
- Iulian Pană (ORCID: https://orcid.org/0000-0003-1368-6219)
- Alina Vlădescu (ORCID: https://orcid.org/0000-0001-5770-4541)
- Jürgen Schmidt (ORCID: https://orcid.org/0000-0002-9377-2119)
- Mihaela Dinu (ORCID: https://orcid.org/0000-0002-3149-6972)
- Senem Büyüksungur (ORCID: https://orcid.org/0000-0001-8438-8193)
- Christina Schmuttermaier
- Harald Klüter (ORCID: https://orcid.org/0000-0002-5460-2897)
- Tuğba Endoğan Tanır (ORCID: https://orcid.org/0000-0002-7241-1437)
- Ioana Maria Marinescu
- Cătălin Vițelaru (ORCID: https://orcid.org/0000-0002-8686-8577)
- Nesrin Hasırcı (ORCID: https://orcid.org/0000-0002-4497-0194)
- Guanhao Li (ORCID: https://orcid.org/0009-0008-1426-4230)
- Quan Liu (ORCID: https://orcid.org/0000-0002-5435-3755)
- L.J. Blum
- Michael Smuglov
- Ernesto Badillo
Institutions
- University of Mannheim (DE)
- Middle East Technical University (TR)
- Heidelberg University (DE)
- German Red Cross (DE)
- University Hospital Heidelberg (DE)
- Innovent (DE)
- Central Institute of Mental Health (DE)
- National Institute of Research and Development for Optoelectronics (RO)
- University Medical Centre Mannheim (DE)
- Near East University (CY)
Publication Details
- Journal
- Journal of Advanced Research
- Published
- 2025-01-27
- DOI
- https://doi.org/10.1016/j.jare.2025.01.045
- Citations
- 5
- Primary Topic
- Bone Tissue Engineering Materials
- Type
- article
- Field-Weighted Citation Impact
- 3.37
Funders
- Tomsk Polytechnic University
- Bundesministerium für Bildung und Forschung
- Türkiye Bilimsel ve Teknolojik Araştırma Kurumu
- China Scholarship Council
- Autoritatea Natională pentru Cercetare Stiintifică
- Unitatea Executiva pentru Finantarea Invatamantului Superior, a Cercetarii, Dezvoltarii si Inovarii