Immune microenvironment features underlying the superior efficacy of neoadjuvant immunochemotherapy over chemotherapy in local advanced gastric cancer
Our study favors neoadjuvant Io+Chemo over Chemo and reveals Io+Chemo can induce the formation of an immune-activated microenvironment that make Io+Chemo superior to Chemo.
Authors
- Yanmei Zhu (ORCID: https://orcid.org/0000-0001-5526-7624)
- Fujing Sun
- Chunyu Li
- Wentao Wang (ORCID: https://orcid.org/0000-0002-9016-7669)
- Ning Zhang (ORCID: https://orcid.org/0000-0001-6306-4819)
- Yong Zhang (ORCID: https://orcid.org/0000-0003-1857-1883)
- Zehua Zhao (ORCID: https://orcid.org/0009-0000-3337-0102)
- Biying Jiang
Institutions
- Dalian University of Technology (CN)
- Liaoning Cancer Hospital & Institute (CN)
- China Medical University (CN)
Publication Details
- Journal
- Frontiers in Immunology
- Published
- 2025-01-27
- DOI
- https://doi.org/10.3389/fimmu.2025.1497004
- Citations
- 5
- Primary Topic
- Gastric Cancer Management and Outcomes
- Type
- article
- Field-Weighted Citation Impact
- 7.59
Funders
- Dalian University of Technology
- Natural Science Foundation of Liaoning Province
- Liaoning Cancer Hospital and Institute