Spontaneous rupture of a giant mature teratoma in the lateral ventricle: a case report

We present the case of an adolescent female patient diagnosed with a ruptured lateral ventricle teratoma. Distinctive radiological and microscopic findings revealed floating oily globules within the ventricles and subarachnoid space. The spontaneous rupture of the teratoma may be attributed to age-dependent hormonal changes, which increase glandular secretion, cyst content volume, and intra-cystic pressure. The patient underwent gross total resection of the tumor, and the subsequent pathological examination confirmed the diagnosis of mature teratoma. Postoperatively, she was managed with routine follow-up without adjuvant chemotherapy or radiotherapy. During the 1-year follow-up period, the patient remained asymptomatic with no evidence of tumor recurrence. Based on this case, we recommend that gross total resection followed by close monitoring, without adjunctive chemotherapy or radiotherapy, can be an effective treatment strategy for patients with similar presentations.

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Publication Details

Journal
Frontiers in Oncology
Published
2025-01-27
DOI
https://doi.org/10.3389/fonc.2024.1493982
Primary Topic
Teratomas and Epidermoid Cysts
Type
article
Field-Weighted Citation Impact
0.00

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article

Spontaneous rupture of a giant mature teratoma in the lateral ventricle: a case report

Yi‐Xiu Xiao, Yuanjie Zou, Liang Liu, Yong Liu et al.
Frontiers in Oncology
Teratomas and Epidermoid Cysts
article

Spontaneous rupture of a giant mature teratoma in the lateral ventricle: a case report

Yi‐Xiu Xiao, Yuanjie Zou, Liang Liu, Yong Liu, Dong Wang, Chunfa Qian, Xinhua Hu, Ran Wang, Liangyuan Geng
article en

Abstract

We present the case of an adolescent female patient diagnosed with a ruptured lateral ventricle teratoma. Distinctive radiological and microscopic findings revealed floating oily globules within the ventricles and subarachnoid space. The spontaneous rupture of the teratoma may be attributed to age-dependent hormonal changes, which increase glandular secretion, cyst content volume, and intra-cystic pressure. The patient underwent gross total resection of the tumor, and the subsequent pathological examination confirmed the diagnosis of mature teratoma. Postoperatively, she was managed with routine follow-up without adjuvant chemotherapy or radiotherapy. During the 1-year follow-up period, the patient remained asymptomatic with no evidence of tumor recurrence. Based on this case, we recommend that gross total resection followed by close monitoring, without adjunctive chemotherapy or radiotherapy, can be an effective treatment strategy for patients with similar presentations.

Frontiers in OncologyVol. 14
Nanjing Brain Hospital (CN), Nanjing Medical University (CN)
National Natural Science Foundation of China, Nanjing Medical University
Good health and well-being
Openalex Percentile: Top 98%
Teratomas and Epidermoid Cysts
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