Study on influencing factors of age-adjusted Charlson comorbidity index in patients with Alzheimer's disease based on machine learning model

The results of this study indicate that the features screened by LASSO regression have the best predictive performance and can significantly improve the predictive ability of aCCI related comorbidities in AD patients. The column chart constructed based on this feature factor provides theoretical guidance for personalized management and precise treatment of AD patients.

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Publication Details

Journal
Frontiers in Medicine
Published
2025-01-27
DOI
https://doi.org/10.3389/fmed.2025.1497662
Primary Topic
Dementia and Cognitive Impairment Research
Type
article
Field-Weighted Citation Impact
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article

Study on influencing factors of age-adjusted Charlson comorbidity index in patients with Alzheimer's disease based on machine learning model

Yiming Liu, Jian Ding, Zheng Long, Min Wang
Frontiers in Medicine
Dementia and Cognitive Impairment Research
article

Study on influencing factors of age-adjusted Charlson comorbidity index in patients with Alzheimer's disease based on machine learning model

Yiming Liu, Jian Ding, Zheng Long, Min Wang
article en

Abstract

The results of this study indicate that the features screened by LASSO regression have the best predictive performance and can significantly improve the predictive ability of aCCI related comorbidities in AD patients. The column chart constructed based on this feature factor provides theoretical guidance for personalized management and precise treatment of AD patients.

Frontiers in MedicineVol. 12
Shandong University (CN), Capital Medical University (CN), Second Hospital of Shandong University (CN), Shanghai Public Health Clinical Center (CN), Qilu Hospital of Shandong University (CN)
Good health and well-being
Openalex Percentile: Top 98%
Dementia and Cognitive Impairment Research
DOIOpen Access PDFOpenAlex
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Study on influencing factors of age-adjusted Charlson comorbidity index in patients with Alzheimer's disease based on machine learning model — Yiming Liu, Jian Ding, et al. · Frontiers in Medicine (2025) | TGRS Research Map | TGRS