Mechanisms of wogonoside in the treatment of atherosclerosis based on network pharmacology, molecular docking, and experimental validation
Wogonoside may be an effective drug monomer for the treatment of atherosclerosis, and its mechanism of action is closely related to the inhibition of the activation of the TLR4/NF-κB signaling pathway.
Authors
- Li Gao (ORCID: https://orcid.org/0000-0003-3963-4847)
- Kang Liang (ORCID: https://orcid.org/0000-0003-3985-7688)
- Yi Liu (ORCID: https://orcid.org/0000-0003-3970-4606)
- Zhaohui Gong
- Chuanjin Luo (ORCID: https://orcid.org/0000-0002-1691-104X)
- Qingmin Chu (ORCID: https://orcid.org/0000-0002-1144-5211)
- Nan Li (ORCID: https://orcid.org/0000-0002-9351-2800)
- Rong Li (ORCID: https://orcid.org/0000-0003-4951-577X)
- Wei Wu (ORCID: https://orcid.org/0000-0003-2935-6660)
- Qiang Xu (ORCID: https://orcid.org/0000-0001-8149-1507)
- Haixin Yang
- He Zhai
Institutions
- Guangzhou University of Chinese Medicine (CN)
- Jinan University (CN)
- First Affiliated Hospital of Guangzhou University of Chinese Medicine (CN)
Publication Details
- Journal
- BMC Complementary Medicine and Therapies
- Published
- 2025-01-27
- DOI
- https://doi.org/10.1186/s12906-025-04760-x
- Citations
- 11
- Primary Topic
- Flavonoids in Medical Research
- Type
- article
- Field-Weighted Citation Impact
- 15.34
Funders
- National Natural Science Foundation of China