THE LIMB BODY WALL COMPLEX: ABOUT TWO CASES - A RARE ANOMALY

Limb Body Wall Complex (LBWC) is a rare and severe congenital anomaly characterized by multiple malformations, including defects in the anterior body wall, internal viscera, spine, central nervous system, and limbs. This article presents two prenatal cases of LBWC diagnosed at 15 and 31 weeks of gestation. Both cases highlight key phenotypic variations, including ectopiacordis, thoracoabdominoschisis, and limb anomalies, with differing placental attachment patterns. Diagnostic considerations, including ultrasound and maternal serum markers, are discussed alongside insights into etiopathogenesis and the uniformly poor prognosis. These cases underscore the importance of early prenatal diagnosis to differentiate LBWC from other anomalies and guide appropriate management, typically medical termination of pregnancy due to the fatal nature of the condition.

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Publication Details

Journal
International Journal of Advanced Research
Published
2024-12-31
DOI
https://doi.org/10.21474/ijar01/20152
Primary Topic
Congenital Anomalies and Fetal Surgery
Type
article
Field-Weighted Citation Impact
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article

THE LIMB BODY WALL COMPLEX: ABOUT TWO CASES - A RARE ANOMALY

Bouchra Fakhir, El. Mahfoudi A., Abderraouf Soummani, L. Boukhani et al.
International Journal of Advanced Research
Congenital Anomalies and Fetal Surgery
article

THE LIMB BODY WALL COMPLEX: ABOUT TWO CASES - A RARE ANOMALY

Bouchra Fakhir, El. Mahfoudi A., Abderraouf Soummani, L. Boukhani, Hamid Asmouki, Ahmed N. Abdallah, Karam Harrou, Abderrahim Aboulfalah, A. Chqormani, B. Ahlam
article en

Abstract

Limb Body Wall Complex (LBWC) is a rare and severe congenital anomaly characterized by multiple malformations, including defects in the anterior body wall, internal viscera, spine, central nervous system, and limbs. This article presents two prenatal cases of LBWC diagnosed at 15 and 31 weeks of gestation. Both cases highlight key phenotypic variations, including ectopiacordis, thoracoabdominoschisis, and limb anomalies, with differing placental attachment patterns. Diagnostic considerations, including ultrasound and maternal serum markers, are discussed alongside insights into etiopathogenesis and the uniformly poor prognosis. These cases underscore the importance of early prenatal diagnosis to differentiate LBWC from other anomalies and guide appropriate management, typically medical termination of pregnancy due to the fatal nature of the condition.

International Journal of Advanced ResearchVol. 12(12)
Openalex Percentile: Top 54%
Congenital Anomalies and Fetal Surgery
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