Nonlinear association between liver fat content and lumbar bone mineral density in overweight and obese individuals: evidence from a large-scale health screening data in China
Among individuals categorized as overweight or obese, elevated levels of LFC were associated with reduced lumbar BMD, particularly noticeable above a threshold of 5.4%. Additionally, various types of inflammatory cells are presumed to exert a substantial mediating influence on the correlation between LFC and lumbar BMD.
Authors
- Zhi Zou
- Yongli Li (ORCID: https://orcid.org/0000-0002-3175-0272)
- Zhonglin Li (ORCID: https://orcid.org/0000-0003-3659-2389)
- Xue Lv (ORCID: https://orcid.org/0009-0009-5298-3604)
- Yongbing Sun (ORCID: https://orcid.org/0000-0001-9142-5466)
- Xiaoling Wu (ORCID: https://orcid.org/0000-0002-7980-3986)
- Ao Liu (ORCID: https://orcid.org/0000-0003-4833-5718)
- Hao Li (ORCID: https://orcid.org/0000-0002-9377-1706)
- Yang Zhou (ORCID: https://orcid.org/0000-0001-5298-234X)
- Jing Wen Zhou (ORCID: https://orcid.org/0000-0001-8336-7278)
- Xin Qi (ORCID: https://orcid.org/0000-0002-5874-7321)
Institutions
- Zhengzhou University (CN)
- Henan Provincial People's Hospital (CN)
- Zhengzhou Central Hospital (CN)
Publication Details
- Journal
- Endocrine
- Published
- 2025-01-27
- DOI
- https://doi.org/10.1007/s12020-025-04168-0
- Primary Topic
- Liver Disease Diagnosis and Treatment
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- National Natural Science Foundation of China
- National Key Research and Development Program of China